What is Flomax (Tamsulosin)?
Flomax is used in the treatment of difficult urination, a common symptom of enlarged prostate. Flomax, and other medications in the class called alpha blockers, work by relaxing bladder neck muscles and muscle fibers in the prostate itself and make it easier to urinate.The Food and Drug Administration (FDA) approved tamsulosin hydrochloride (HCL) under the brand name Flomax in 1997.
However, the FDA has not approved tamsulosin for use in women or children, although some doctors use it off-label in these patients.
Flomax is in a group of drugs called alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. Flomax relaxes the muscles in the prostate and bladder neck, making it easier to urinate.
Flomax is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).
Flomax may also be used for other purposes not listed in this medication guide.
Flomax Interactions
It's always important to share with your doctor and pharmacist all prescription, non-prescription, illegal, recreational, herbal, nutritional, or dietary drugs you're taking.You shouldn't take tamsulosin if you're also taking the following drugs:
Medications for fungal infections like Sporanox (itraconazole), Noxafil (posaconazole), Vfend (voriconazole), and Nizoral (ketoconazole)
HIV/AIDS medications like Kaletra (lopinavir/ritonavir), Norvir (ritonavir), and Stribild (cobicistat/elvitegravir/emtricitabine/tenofovir)
Victrelis (Boceprevir)
Antibiotics like chloramphenicol, Biaxin (clarithromycin) and Ketek (telithromycin)
Vaprisol (conivaptan)
Gengraf, Neoral, or Sandimmune (cyclosporine)
Rescriptor (delarvirdine), Lexiva (fosamprenavir)
Faverin, Fevarin, Floxyfral, Luvox (fluvoxamine)
Cancer medications like Gleevec (imatinib)
Serzone (nefazodone)
Incivek (telaprevir)
You should also avoid taking tamsulosin if you are taking any of the following:
Other alpha-blocker medications for prostate conditions like Minipress (prazosin), Rapaflo (silodosin), Hytrin (terazosin)
Quinaglute, Quinidec (quinidine)
Drugs for depression called selective serotonin reuptake inhibitors (SSRIs) like Zoloft (sertraline) or Prozac (fluoxetine)
Drugs for depression called tricyclic antidepressants (TCAs) like Paxil (paroxetine), Anafranil (clomipramine), and Norpramin (desipramine)
Antibiotics like Vibramycin (doxycycline); EryTab, E.E.S., or Erythrocin (erythromycin); Vigamox (moxifloxacin)
Cocaine
Medications for irregular heartbeat like Cordarone, Nexterone, or Pacerone (amiodarone),444 or Multaq (dronedarone)
Benadryl (diphenhydramine)
Medications for mood like Haldol (haloperidol) or Clozaril (clozapine)
Talk to your doctor about any alternatives to tamsulosin if you're taking any of these medications.
Pregnancy and Flomax
Flomax is generally considered safe to take during pregnancy.Regardless, you should tell your doctor if you're pregnant or plan to become pregnant before taking this medication.
You should also alert your physician if you're breastfeeding or plan to breastfeed.
It's not recommended that breastfeeding mothers take this medication.
Drug Descriptions
Tamsulosin hydrochloride is an antagonist of alpha1A adrenoceptors in the prostate.Tamsulosin hydrochloride is (-)-(R)-5-[2-[[2-(o-Ethoxyphenoxy) ethyl]amino]propyl]-2-methoxybenzenesulfonamide, monohydrochloride. Tamsulosin hydrochloride is a white crystalline powder that melts with decomposition at approximately 230°C. It is sparingly soluble in water and methanol, slightly soluble in glacial acetic acid and ethanol, and practically insoluble in ether.
The empirical formula of tamsulosin hydrochloride is C20H28N2O5S • HCl. The molecular weight of tamsulosin hydrochloride is 444.98. Its structural formula is:
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